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Concept information

disease > skin appendages disease > skin disease > hypereosinophilic syndrome
disease > cardiovascular disease > heart disease > cardiomyopathy > hypereosinophilic syndrome
disease > hemopathy > coagulopathy > hypereosinophilic syndrome
disease > nervous system diseases > hypereosinophilic syndrome
disease > respiratory disease > lung disease > hypereosinophilic syndrome
disease > hemopathy > eosinophilia > hypereosinophilic syndrome
disease > digestive diseases > hepatic disease > hepatosplenomegaly > hypereosinophilic syndrome
disease > splenic disease > hepatosplenomegaly > hypereosinophilic syndrome

Preferred term

hypereosinophilic syndrome  

Definition(s)

  • Hypereosinophilic syndrome is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow.HES is a diagnosis of exclusion, after clonal eosinophilia (such as FIP1L1-PDGFRA-fusion induced hypereosinophelia and leukemia) and reactive eosinophilia (in response to infection, autoimmune disease, atopy, hypoadrenalism, tropical eosinophilia, or cancer) have been ruled out.There are some associations with chronic eosinophilic leukemia as it shows similar characteristics and genetic defects. (Wikipedia)

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URI

http://data.loterre.fr/ark:/67375/VH8-D1H1BVZW-X

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