Concept information
Preferred term
protease inhibitor
Definition(s)
- Protease inhibitors (PIs) are a class of antiviral drugs that are widely used to treat HIV/AIDS and hepatitis C. Protease inhibitors prevent viral replication by selectively binding to viral proteases (e.g. HIV-1 protease) and blocking proteolytic cleavage of protein precursors that are necessary for the production of infectious viral particles.
Broader concept(s)
In other languages
-
French
URI
http://data.loterre.fr/ark:/67375/INS-VRMZSBHZ-D
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